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The breakthrough: Malarial Vaccine

Malaria is one of the deadliest diseases killing almost 400,000 humans in just a year. It is most common in Sub-Saharan Africa and majorly affects children.

According to the World Health Organization, around 229 million cases of Malaria were recorded worldwide, and about 409,000 deaths were recorded in the year 2019.

Malaria is a life-threatening disease caused by the malarial parasite. The vector-borne disease is transmitted from one person to another through the mosquito bite. To overcome this disease, researchers say that vaccines could be one of the significant breaks through and will substantially impact human health.

According to the Professor of vaccinology at the University of Oxford and Director of Jenner Institute, this is the first vaccine against Malaria showing 75 % efficacy that reached the World health organization. Earlier vaccines were nearly 55 % efficient only.

He also said that trials for malarial vaccines began way before the COVID Vaccines and the research for malarial vaccine further helped develop the COVID Vaccine.

He further added that it took a long time to develop the malarial vaccine compared to that of the COVID Vaccine since the Coronavirus has few genes and there are thousands of genes in Malaria Also, a very effective immune response is needed to fight off the Malaria.

The researchers predicted that the malarial vaccine showed 77 % efficacy in the higher dose group and 71 % efficacy in lower dose groups.
The Professor in parasitology, who is also the chief researcher of the Clinical Research Unit of Nanoro, Burkina Faso, said that the results were terrific. The efficacy level seen was unpredictable.

They are further looking forward to conducting Phase III trials to check the safety and efficacy of the vaccines, after which they can be produced and distributed on a large scale, which is required for that region urgently.

Many companies like Serum Institute of India, Biotechnology company Novavax came forward to help in the production of the Malarial vaccine. Hence, the malarial vaccine could significantly reduce the number of deaths caused due to Malaria.